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3-Day Hands-On Workshop on Bioinformatics Models

This workshop introduces participants to core bioinformatics concepts and analytical models, focusing on sequence analysis, evolutionary relationships, and molecular interaction theory. The program emphasizes conceptual understanding, guided exercises, and clear documentation, suitable for beginners in computational biology.


Day 1: Biological Databases & Sequence Analysis

Concepts Covered

  • Introduction to bioinformatics and its applications

  • Overview of biological sequence databases

    • NCBI

    • UniProt

    • EMBL (conceptual overview)

  • Types of sequences: DNA, RNA, and protein

Hands-On Exercises

  • BLAST theory

    • Local alignment principles

    • E-value, score, and identity

  • Guided protein and DNA sequence search exercises

  • Interpretation of BLAST output tables and alignments

Skills Gained

  • Navigating sequence databases

  • Understanding similarity and homology

  • Documenting sequence analysis results


Day 2: Phylogenetic Analysis & Evolutionary Models

Concepts Covered

  • Molecular evolution and phylogenetics

  • Types of phylogenetic trees

    • Rooted vs unrooted

    • Cladograms vs phylograms

  • Distance-based vs character-based methods (introductory)

Hands-On Planning

  • Phylogenetic tree construction planning

    • Paper-based tree drawing

    • Use of simple offline tools (demo-based)

  • Selection of sequences and alignment concepts

  • Interpretation of evolutionary relationships

Learning Outcome

  • Understanding how sequence similarity reflects evolutionary history

  • Ability to explain tree topology and branching patterns


Day 3: Molecular Docking Theory & Interaction Analysis

Concepts Covered

  • Introduction to molecular docking and structure-based analysis

  • Protein–ligand interactions and binding energy concepts

  • Applications in drug discovery and molecular biology

Hands-On / Guided Activities

  • Molecular docking theory walkthrough

  • Binding site identification

    • Active site recognition

    • Key residues involved in interactions

  • Visualization of protein–ligand interactions (conceptual/demo-based)

Outcome

  • Documentation of docking workflow and observations

  • Understanding docking results and limitations

  • Preparation of a bioinformatics exercise report


Workshop Outcomes

By the end of this workshop, participants will:

  • Use biological databases for sequence retrieval

  • Perform and interpret BLAST searches

  • Understand phylogenetic tree construction and interpretation

  • Grasp molecular docking principles and binding site concepts

  • Document bioinformatics analyses clearly


Who Can Attend

  • Life science, biotechnology & bioinformatics students

  • Research interns and beginners in computational biology

  • Educators and laboratory professionals transitioning to bioinformatics

  • Anyone interested in biological data analysis


📌 Limited Seats Available

Build strong foundations in bioinformatics through structured models and guided exercises.

👉 Register now to secure your seat
📩 Click the Register button for schedule, fees, tools used, and certification details.